Duraplasty in Traumatic Thoracic Spinal Cord Injury: Impact on Spinal Cord Hemodynamics, Tissue Metabolism, Histology, and Behavioral Recovery Using a Porcine Model

This study uses a Yucatan model of traumatic spinal-cord-injury to investigate how duraplasty affects spinal cord pressure, hemodynamics, tissue metabolism, histology, and behavioral recovery. The findings provide translational information relevant to surgical decompression following acute spinal cord injury.

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Citation:
Streijger, F., Kim, K.-T., So, K., Manouchehri, N., Shortt, K., Okon, E. B., Morrison, C., Fong, A., Gupta, R., Allard Brown, A., Tigchelaar, S., Sun, J., Liu, E., Keung, M., Daly, C. D., Cripton, P. A., Sekhon, M. S., Griesdale, D. E., & Kwon, B. K. (2021). Duraplasty in traumatic thoracic spinal cord injury: Impact on spinal cord hemodynamics, tissue metabolism, histology, and behavioral recovery using a porcine model. Journal of Neurotrauma, 38(21), 2937–2955. https://doi.org/10.1089/neu.2021.0084