Pigs in Toxicology: Breed Differences in Metabolism and Background Findings 

This review examines the use of pigs and miniature swine in toxicology, including their biological characteristics, background findings, research applications, and value as alternatives to traditional non-rodent models. It provides practical context for selecting and interpreting porcine models in safety-assessment programs.

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Citation:
Helke, K. L., Nelson, K. N., Sargeant, A. M., Jacob, B., McKeag, S., Haruna, J., Vemireddi, V., Greeley, M., Brocksmith, D., Navratil, N., Stricker-Krongrad, A., & Hollinger, C. (2016). Pigs in toxicology. Toxicologic Pathology, 44(4), 575–590. https://doi.org/10.1177/0192623316639389